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Self-awareness in humans is a natural tendency. This self-awareness is processed by the human brain based on various inputs received from the body’s sensory systems. Mimicking this functionality on an electronic platform—also known as neuromorphic computing—can lead to highly intelligent machines that could be utilized in many day-to-day activities, ranging from autonomous cars to smart navigation assistants. However, neuromorphic computing faces several challenges, including energy efficiency, reliability, and security. In the REACT MSCA Doctoral Network project, we aim to develop a neuromorphic platform that is self-aware in terms of energy efficiency, security, and reliability. The project seeks to train 15 early-stage PhD researchers in interdisciplinary domains such as materials science, device physics, computer architecture, hardware prototyping, compilers, simulation and emulation frameworks, security, reliability, and verifiability.